Yes, naltrexone is considered safe for most people and has been approved by the U.S. Food and Drug Administration (FDA) since 1994 for treating alcohol dependence and opioid addiction.
However, it should not be used by individuals who are currently using opioids, as it can cause sudden opioid withdrawal symptoms. Additionally, people with acute hepatitis or severe liver disease should avoid naltrexone because it can put additional strain on the liver. While naltrexone is generally safe, it’s important to take it as prescribed and follow your healthcare provider’s recommendations.