A targeted approach (also known as The Sinclair Method or TSM) is one effective way to use naltrexone for alcohol addiction. The method is distinct from traditional addiction treatments because it allows individuals to drink while using the medication. Here’s a detailed breakdown of how it works:
Key Components of Targeted Naltrexone Treatment:
Take naltrexone before drinking: The critical aspect of targeted naltrexone treatment is taking naltrexone one hour before consuming alcohol. Naltrexone blocks the brain's opioid receptors, which are responsible for triggering the release of endorphins (natural pleasure chemicals) when you drink. By taking naltrexone before drinking, the pleasurable effects of alcohol are significantly reduced.
Drink as usual: Unlike traditional abstinence-based treatments, targeted naltrexone treatment allows individuals to continue drinking, but they will notice that alcohol becomes less enjoyable because naltrexone blocks the euphoric or "buzzed" feeling associated with alcohol consumption. Over time, this leads to:
Less desire to drink: Drinking becomes less rewarding, and cravings for alcohol diminish.
Reduction in alcohol consumption: Many people naturally drink less as the brain stops associating alcohol with a pleasurable reward.
With consistent use, individuals notice that they no longer think about alcohol as often and feel less compulsion to drink excessively.
Continued use is crucial: Naltrexone must be taken every time before drinking, even if someone only plans to have a small amount of alcohol. Skipping the medication while drinking can reinforce the pleasurable association, counteracting the treatment.
Not for abstinence, but reduction: targeted naltrexone treatment is not necessarily aimed at achieving complete abstinence right away. Instead, it’s focused on reducing harmful drinking patterns by reducing cravings and preoccupation with thoughts about alcohol. For some individuals, this method leads to eventual abstinence, but for others, it results in controlled drinking.